4S1T
Crystal structure of the mutant I26A/N52A of the endoribonuclease from human coronavirus 229E
Summary for 4S1T
Entry DOI | 10.2210/pdb4s1t/pdb |
Descriptor | Uridylate-specific endoribonuclease, PHOSPHATE ION (3 entities in total) |
Functional Keywords | hcov-229e, endoribonuclease, trimeric nsp15, double mutation, hydrolase |
Biological source | Human coronavirus 229E (HCoV-229E) |
Cellular location | Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : P0C6X1 |
Total number of polymer chains | 6 |
Total formula weight | 233503.23 |
Authors | |
Primary citation | Huo, T.,Liu, X.,Yang, C.,Rao, Z. Crystal structure and mutational analysis of the endoribonuclease from human coronavirus 229E To be Published, |
Experimental method | X-RAY DIFFRACTION (2.504 Å) |
Structure validation
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