4S1T
Crystal structure of the mutant I26A/N52A of the endoribonuclease from human coronavirus 229E
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 401 |
| Chain | Residue |
| A | HIS235 |
| A | GLY248 |
| A | HIS250 |
| A | LYS291 |
| A | THR342 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 401 |
| Chain | Residue |
| B | THR342 |
| B | HOH538 |
| B | HIS235 |
| B | GLY248 |
| B | HIS250 |
| B | LYS291 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 C 401 |
| Chain | Residue |
| C | HIS250 |
| C | LYS291 |
| C | THR342 |
| C | HOH504 |
| C | HOH591 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 D 401 |
| Chain | Residue |
| D | HIS235 |
| D | HIS250 |
| D | LYS291 |
| D | THR342 |
| D | HOH521 |
| D | HOH593 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 E 401 |
| Chain | Residue |
| E | HIS235 |
| E | GLY248 |
| E | HIS250 |
| E | LYS291 |
| E | HOH598 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 F 401 |
| Chain | Residue |
| F | HIS235 |
| F | GLY248 |
| F | HIS250 |
| F | LYS291 |
| F | THR342 |
| F | HOH538 |
| F | HOH584 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 360 |
| Details | Domain: {"description":"Nsp15 N-terminal oligomerization","evidences":[{"source":"PROSITE-ProRule","id":"PRU01305","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 840 |
| Details | Domain: {"description":"NendoU","evidences":[{"source":"PROSITE-ProRule","id":"PRU01303","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01303","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
