4S1T
Crystal structure of the mutant I26A/N52A of the endoribonuclease from human coronavirus 229E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Uridylate-specific endoribonuclease | polymer | 349 | 38822.2 | 6 | UniProt (P0C6X1) Pfam (PF19219) Pfam (PF19216) Pfam (PF19215) | Human coronavirus 229E (HCoV-229E) | nsp15, Nonstructural protein 15 |
| 2 | G, H, I, J, K... (A, B, C, D, E...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 3 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 519 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 348 (UniProt: P0C6X1)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 26 | Ile 6136 | engineered mutation |
| Ala 52 | Asn 6162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 232933.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 569.8 | |
| All* | Total formula weight | 233503.2 |
