4RXD
T. Brucei Farnesyl Diphosphate Synthase Complexed with Risedronate
Summary for 4RXD
| Entry DOI | 10.2210/pdb4rxd/pdb |
| Related | 4RXC |
| Descriptor | Farnesyl pyrophosphate synthase, MAGNESIUM ION, 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, ... (4 entities in total) |
| Functional Keywords | transferase |
| Biological source | Trypanosoma brucei |
| Total number of polymer chains | 3 |
| Total formula weight | 134495.29 |
| Authors | Cao, R.,Liu, Y.-L.,Oldfield, E. (deposition date: 2014-12-10, release date: 2015-04-15, Last modification date: 2023-09-20) |
| Primary citation | Liu, Y.L.,Cao, R.,Wang, Y.,Oldfield, E. Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries. ACS Med Chem Lett, 6:349-354, 2015 Cited by PubMed: 25815158DOI: 10.1021/ml500528x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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