4RXD

T. Brucei Farnesyl Diphosphate Synthase Complexed with Risedronate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Farnesyl pyrophosphate synthase	polymer	390	44475.7	3	UniProt (Q86C09)	Trypanosoma brucei
2	D, E, F, H, I... (A, B, C)	MAGNESIUM ION	non-polymer		24.3	9	Chemie (MG)
3	G, K, L (A, B, C)	1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID	non-polymer		283.1	3	Chemie (RIS)
4	P, Q, R (A, B, C)	water	water		18.0	484	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 367 (UniProt: Q86C09)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	133427.2
Non-Polymers*	Number of molecules	12
	Total formula weight	1068.1
All*	Total formula weight	134495.3

*Water molecules are not included.