4RXC
T. Brucei Farnesyl Diphosphate Synthase Complexed with Homorisedronate BPH-6
Summary for 4RXC
Entry DOI | 10.2210/pdb4rxc/pdb |
Related | 4RXD |
Descriptor | Farnesyl pyrophosphate synthase, [1-hydroxy-3-(pyridin-3-yl)propane-1,1-diyl]bis(phosphonic acid), MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Trypanosoma brucei |
Total number of polymer chains | 2 |
Total formula weight | 90334.47 |
Authors | Cao, R.,Liu, Y.-L.,Oldfield, E. (deposition date: 2014-12-09, release date: 2015-04-15, Last modification date: 2024-02-28) |
Primary citation | Liu, Y.L.,Cao, R.,Wang, Y.,Oldfield, E. Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries. ACS Med Chem Lett, 6:349-354, 2015 Cited by PubMed: 25815158DOI: 10.1021/ml500528x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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