4RXC
T. Brucei Farnesyl Diphosphate Synthase Complexed with Homorisedronate BPH-6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004161 | molecular_function | dimethylallyltranstransferase activity |
| A | 0004337 | molecular_function | (2E,6E)-farnesyl diphosphate synthase activity |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004161 | molecular_function | dimethylallyltranstransferase activity |
| B | 0004337 | molecular_function | (2E,6E)-farnesyl diphosphate synthase activity |
| B | 0004659 | molecular_function | prenyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HRX A 401 |
| Chain | Residue |
| A | ASP103 |
| A | HRX405 |
| A | HOH577 |
| A | ASP107 |
| A | ARG112 |
| A | GLN172 |
| A | LYS212 |
| A | TYR216 |
| A | MG402 |
| A | MG403 |
| A | MG404 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP103 |
| A | ASP107 |
| A | HRX401 |
| A | MG403 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 403 |
| Chain | Residue |
| A | ASP103 |
| A | ASP107 |
| A | HRX401 |
| A | MG402 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 404 |
| Chain | Residue |
| A | HRX401 |
| A | HRX405 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE HRX A 405 |
| Chain | Residue |
| A | PHE251 |
| A | GLN252 |
| A | ASP255 |
| A | LYS269 |
| A | HRX401 |
| A | MG404 |
| A | MG406 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 406 |
| Chain | Residue |
| A | ASP255 |
| A | HRX405 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE HRX B 401 |
| Chain | Residue |
| B | TYR99 |
| B | ASP103 |
| B | ASP107 |
| B | ARG112 |
| B | THR168 |
| B | GLN172 |
| B | LYS212 |
| B | TYR216 |
| B | MG402 |
| B | MG403 |
| B | MG404 |
| B | HRX405 |
| B | HOH522 |
| B | HOH548 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 402 |
| Chain | Residue |
| B | ASP103 |
| B | ASP107 |
| B | HRX401 |
| B | MG403 |
| B | HOH548 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 403 |
| Chain | Residue |
| B | ASP103 |
| B | ASP107 |
| B | HRX401 |
| B | MG402 |
| B | HOH568 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG B 404 |
| Chain | Residue |
| B | HRX401 |
| B | HRX405 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE HRX B 405 |
| Chain | Residue |
| B | PHE251 |
| B | GLN252 |
| B | ASP255 |
| B | LYS269 |
| B | HRX401 |
| B | MG404 |
| B | MG406 |
| B | HOH560 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 406 |
| Chain | Residue |
| B | ASP255 |
| B | HRX405 |
| B | HOH565 |
Functional Information from PROSITE/UniProt
