4RXC

T. Brucei Farnesyl Diphosphate Synthase Complexed with Homorisedronate BPH-6

Summary for 4RXC

Entry DOI	10.2210/pdb4rxc/pdb
Related	4RXD
Descriptor	Farnesyl pyrophosphate synthase, [1-hydroxy-3-(pyridin-3-yl)propane-1,1-diyl]bis(phosphonic acid), MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	transferase
Biological source	Trypanosoma brucei
Total number of polymer chains	2
Total formula weight	90334.47
Authors	Cao, R.,Liu, Y.-L.,Oldfield, E. (deposition date: 2014-12-09, release date: 2015-04-15, Last modification date: 2024-02-28)
Primary citation	Liu, Y.L.,Cao, R.,Wang, Y.,Oldfield, E. Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries. ACS Med Chem Lett, 6:349-354, 2015 Cited by PubMed: 25815158 DOI: 10.1021/ml500528x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.31 Å)

Structure validation