4RIB
FAN1 Nuclease bound to 5' phosphorylated p(dT) single flap DNA
Summary for 4RIB
Entry DOI | 10.2210/pdb4rib/pdb |
Related | 4RI8 4RI9 4RIA 4RIC 4RID |
Descriptor | Fanconi-associated nuclease 1, DNA (5'-D(P*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*TP*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*GP*GP*AP*GP*TP*CP*T)-3'), ... (5 entities in total) |
Functional Keywords | nuclease, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q9Y2M0 |
Total number of polymer chains | 8 |
Total formula weight | 176064.46 |
Authors | Pavletich, N.P.,Wang, R. (deposition date: 2014-10-05, release date: 2014-12-03, Last modification date: 2024-02-28) |
Primary citation | Wang, R.,Persky, N.S.,Yoo, B.,Ouerfelli, O.,Smogorzewska, A.,Elledge, S.J.,Pavletich, N.P. DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1. Science, 346:1127-1130, 2014 Cited by PubMed: 25430771DOI: 10.1126/science.1258973 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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