4REB

Structural Insights into 5' Flap DNA Unwinding and Incision by the Human FAN1 Dimer

Summary for 4REB

• Entry DOI: 10.2210/pdb4reb/pdb
• Related: 4REA 4REC
• Descriptor: DNA (5'-D(P*GP*TP*GP*GP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*CP*GP*AP*GP*CP*GP*CP*TP*CP*GP*CP*CP*AP*CP*G)-3'), DNA (5'-D(P*GP*CP*TP*CP*GP*CP*CP*AP*CP*G)-3'), ... (5 entities in total)
• Functional Keywords: hjc, tpr, sap, structure specific nuclease, fancid2, nucleus, hydrolase-dna complex, hydrolase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus : Q9Y2M0
• Total number of polymer chains: 5
• Total formula weight: 159548.22

Authors

Zhao, Q.,Xue, X.,Longerich, S.,Sung, P.,Xiong, Y. (deposition date: 2014-09-22, release date: 2014-12-24, Last modification date: 2024-02-28)

• Primary citation: Zhao, Q.,Xue, X.,Longerich, S.,Sung, P.,Xiong, Y.; Structural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.; Nat Commun, 5:5726-5726, 2014; PubMed: 25500724; DOI: 10.1038/ncomms6726

Experimental method

X-RAY DIFFRACTION (4.2 Å)