4REB

Structural Insights into 5' Flap DNA Unwinding and Incision by the Human FAN1 Dimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004518	molecular_function	nuclease activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0036297	biological_process	interstrand cross-link repair
H	0003676	molecular_function	nucleic acid binding
H	0004518	molecular_function	nuclease activity
H	0016788	molecular_function	hydrolase activity, acting on ester bonds
H	0036297	biological_process	interstrand cross-link repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SM A 1101

Chain	Residue
A	GLU390
A	GLU435

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SM H 1101

Chain	Residue
H	GLU390
H	GLU435

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9I2N0

Chain	Residue	Details
A	GLU834
A	ALA960
A	GLU975
A	VAL976
H	GLU834
H	ALA960
H	GLU975
H	VAL976

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