4REB

Structural Insights into 5' Flap DNA Unwinding and Incision by the Human FAN1 Dimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0004518	molecular_function	nuclease activity
A	0016788	molecular_function	hydrolase activity, acting on ester bonds
A	0036297	biological_process	interstrand cross-link repair
H	0003676	molecular_function	nucleic acid binding
H	0004518	molecular_function	nuclease activity
H	0016788	molecular_function	hydrolase activity, acting on ester bonds
H	0036297	biological_process	interstrand cross-link repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SM A 1101

Chain	Residue
A	GLU390
A	GLU435

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SM H 1101

Chain	Residue
H	GLU390
H	GLU435

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	224
Details	Domain: {"description":"VRR-NUC"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	50
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9I2N0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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