4QMG

The Structure of MTDH-SND1 Complex Reveals Novel Cancer-Promoting Interactions

Summary for 4QMG

Entry DOI	10.2210/pdb4qmg/pdb
Related	2E6N 2HQE 2HQX 3BDL 3OMC 3OMG
Descriptor	Staphylococcal nuclease domain-containing protein 1, Protein LYRIC, SULFATE ION, ... (6 entities in total)
Functional Keywords	sn domains, oligonucleotide/oligosaccharide binding-fold (ob-fold), dna/rna-binding, mirna-mediated silencing, nuclease, breast cancer, tumorigenesis, snd1, mtdh, transcription
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q7KZF4 Endoplasmic reticulum membrane; Single-pass membrane protein: Q86UE4
Total number of polymer chains	10
Total formula weight	208065.20
Authors	Guo, F.,Stanevich, V.,Wan, L.,Satyshur, K.,Kang, Y.,Xing, Y. (deposition date: 2014-06-16, release date: 2014-10-08)
Primary citation	Guo, F.,Wan, L.,Zheng, A.,Stanevich, V.,Wei, Y.,Satyshur, K.A.,Shen, M.,Lee, W.,Kang, Y.,Xing, Y. Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex. Cell Rep, 8:1704-1713, 2014 Cited by PubMed: 25242325 DOI: 10.1016/j.celrep.2014.08.033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.701 Å)

Structure validation