4Q4M

tRNA-Guanine Transglycosylase (TGT) in Complex with 6-Amino-4-phenyl-1,2-dihydro-1,3,5-triazin-2-one

Summary for 4Q4M

• Entry DOI: 10.2210/pdb4q4m/pdb
• Related: 4Q4O 4Q4P 4Q4Q 4Q4R 4Q4S
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-4-phenyl-1,3,5-triazin-2(1H)-one, ... (5 entities in total)
• Functional Keywords: transferase, preq1, trna, guanine exchange enzyme, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43491.83

Authors

Neeb, M.,Heine, A.,Klebe, G. (deposition date: 2014-04-15, release date: 2015-06-10, Last modification date: 2023-09-20)

• Primary citation: Neeb, M.,Hohn, C.,Heine, A.,Diederich, F.,Klebe, G.; 5-Azacytosines as a Novel Scaffold to Inhibit Z. mobilis TGT with Expected Improved Bioavailability and Synthetic Accessibility; To be Published,

Experimental method

X-RAY DIFFRACTION (1.621 Å)