4Q2G
CRYSTAL STRUCTURE OF AN INTRAMEMBRANE CDP-DAG SYNTHETASE CENTRAL FOR PHOSPHOLIPID BIOSYNTHESIS (S200C/S223C, inactive mutant)
Summary for 4Q2G
Entry DOI | 10.2210/pdb4q2g/pdb |
Related | 4Q2E |
Descriptor | Phosphatidate cytidylyltransferase, MERCURY (II) ION, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | intramembrane enzyme, cdsa fold, phospholipid biosynthesis lipid metabolism, ctp and phosphatidic acid binding, nucleotidyltransferase, membrane, transferase |
Biological source | Thermotoga maritima MSB8 |
Cellular location | Cell membrane; Multi-pass membrane protein (By similarity): Q9X1B7 |
Total number of polymer chains | 2 |
Total formula weight | 66117.56 |
Authors | |
Primary citation | Liu, X.,Yin, Y.,Wu, J.,Liu, Z. Structure and mechanism of an intramembrane liponucleotide synthetase central for phospholipid biosynthesis Nat Commun, 5:4244-4244, 2014 Cited by PubMed: 24968740DOI: 10.1038/ncomms5244 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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