4PSG

Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP

Summary for 4PSG

• Entry DOI: 10.2210/pdb4psg/pdb
• Related: 4ein 4ez8 4g9u 4iqb 4iqq 4irr
• Descriptor: Thymidylate synthase, 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate) (3 entities in total)
• Functional Keywords: enzyme, methyltransferase, nucleotide biosynthesis, protein dimer, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Caenorhabditis elegans (roundworm)
• Total number of polymer chains: 2
• Total formula weight: 72358.20

Authors

Wilk, P.,Jarmula, A.,Rode, W. (deposition date: 2014-03-07, release date: 2015-02-18, Last modification date: 2024-02-28)

• Primary citation: Dowiercia, A.,Wilk, P.,Rypniewski, W.,Rode, W.,Jarmua, A.; Crystal Structure of C.elegans Thymidylate Synthase in complex with an inhibitor N(4)OHdCMP; To be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)