4OMO
Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E
Summary for 4OMO
Entry DOI | 10.2210/pdb4omo/pdb |
Related | 3FJ5 4HVU 4HVV 4HVW 4JZ3 4JZ4 |
Descriptor | Proto-oncogene tyrosine-protein kinase Src, NICKEL (II) ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | beta-barrel sandwich, kinase, proline rich motifs, transferase |
Biological source | Gallus gallus (bantam,chickens) |
Cellular location | Cell membrane : P00523 |
Total number of polymer chains | 2 |
Total formula weight | 14168.66 |
Authors | Camara-Artigas, A.,Bacarizo, J. (deposition date: 2014-01-27, release date: 2014-12-10, Last modification date: 2023-09-20) |
Primary citation | Bacarizo, J.,Martinez-Rodriguez, S.,Martin-Garcia, J.M.,Andujar-Sanchez, M.,Ortiz-Salmeron, E.,Neira, J.L.,Camara-Artigas, A. Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation. Plos One, 9:e113224-e113224, 2014 Cited by PubMed: 25490095DOI: 10.1371/journal.pone.0113224 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.04 Å) |
Structure validation
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