4NO7
Human Glucokinase in complex with a nanomolar activator.
Summary for 4NO7
Entry DOI | 10.2210/pdb4no7/pdb |
Related | 1V4S 3ID8 |
Descriptor | Glucokinase, alpha-D-glucopyranose, (2R)-2-[3-chloro-4-(methylsulfonyl)phenyl]-3-[(1R)-3-oxocyclopentyl]-N-(pyrazin-2-yl)propanamide, ... (4 entities in total) |
Functional Keywords | kinase, pancreas, transferase-transferase activator complex, transferase/transferase activator |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 53598.24 |
Authors | Petit, P.,Ferry, G.,Antoine, M.,Boutin, J.A.,Kotschy, A.,Perron-Sierra, F.,Mamelli, L.,Vuillard, L. (deposition date: 2013-11-19, release date: 2014-10-29, Last modification date: 2023-09-20) |
Primary citation | Petit, P.,Antoine, M.,Ferry, G.,Boutin, J.A.,Lagarde, A.,Gluais, L.,Vincentelli, R.,Vuillard, L. The active conformation of human glucokinase is not altered by allosteric activators. Acta Crystallogr. D Biol. Crystallogr., 67:929-935, 2011 Cited by PubMed: 22101819DOI: 10.1107/S0907444911036729 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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