3ID8

Ternary complex of human pancreatic glucokinase crystallized with activator, glucose and AMP-PNP

Summary for 3ID8

Entry DOI	10.2210/pdb3id8/pdb
Related	1V4S 3F9M 3FGU 3IDH
Descriptor	Glucokinase, alpha-D-glucopyranose, 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, ... (7 entities in total)
Functional Keywords	glucokinase, hexokinase iv, atp-binding, diabetes mellitus, disease mutation, glycolysis, kinase, nucleotide-binding, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	54095.35
Authors	Petit, P.,Gluais, L.,Lagarde, A.,Boutin, J.A.,Ferry, G.,Vuillard, L. (deposition date: 2009-07-20, release date: 2010-07-28, Last modification date: 2023-11-01)
Primary citation	Petit, P.,Antoine, M.,Ferry, G.,Boutin, J.A.,Lagarde, A.,Gluais, L.,Vincentelli, R.,Vuillard, L. The active conformation of human glucokinase is not altered by allosteric activators Acta Crystallogr.,Sect.D, 67:929-935, 2011 Cited by PubMed: 22101819 DOI: 10.1107/S0907444911036729 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation