3ID8
Ternary complex of human pancreatic glucokinase crystallized with activator, glucose and AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glucokinase | polymer | 470 | 52996.2 | 1 | UniProt (P35557) Pfam (PF00349) Pfam (PF03727) | Homo sapiens (human) | Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D |
| 2 | B (A) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 3 | C (A) | 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE | non-polymer | 349.4 | 1 | Chemie (MRK) | |||
| 4 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | G (A) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 12 - 465 (UniProt: P35557)
| PDB | External Database | Details |
|---|---|---|
| Met -4 | - | expression tag |
| Gly -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| Glu 4 | - | expression tag |
| Asn 5 | - | expression tag |
| Leu 6 | - | expression tag |
| Tyr 7 | - | expression tag |
| Phe 8 | - | expression tag |
| Gln 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Met 11 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52996.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1099.2 | |
| All* | Total formula weight | 54095.3 |
