4LOT

C1s CUB2-CCP1-CCP2

Summary for 4LOT

Entry DOI	10.2210/pdb4lot/pdb
Related	4LMF 4LOR 4LOS
Descriptor	Complement C1s subcomponent heavy chain (1 entity in total)
Functional Keywords	cub domain, ccp domain, complement c1s, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	27508.74
Authors	Wallis, R.,Venkatraman Girija, U.,Moody, P.C.E.,Marshall, J.E. (deposition date: 2013-07-13, release date: 2013-08-07, Last modification date: 2013-09-04)
Primary citation	Venkatraman Girija, U.,Gingras, A.R.,Marshall, J.E.,Panchal, R.,Sheikh, M.A.,Gal, P.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.,Wallis, R. Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation. Proc.Natl.Acad.Sci.USA, 110:13916-13920, 2013 Cited by PubMed: 23922389 DOI: 10.1073/pnas.1311113110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.92 Å)

Structure validation