4LL4
The structure of the TRX and TXNIP complex
Summary for 4LL4
Entry DOI | 10.2210/pdb4ll4/pdb |
Related | 4GFX 4LL1 |
Descriptor | Thioredoxin-interacting protein, Thioredoxin (3 entities in total) |
Functional Keywords | arrestin-like domain, antitumor protein-protein binding complex, antitumor protein/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): Q9H3M7 Nucleus: P10599 |
Total number of polymer chains | 4 |
Total formula weight | 93511.82 |
Authors | |
Primary citation | Hwang, J.,Suh, H.W.,Jeon, Y.H.,Hwang, E.,Nguyen, L.T.,Yeom, J.,Lee, S.G.,Lee, C.,Kim, K.J.,Kang, B.S.,Jeong, J.O.,Oh, T.K.,Choi, I.,Lee, J.O.,Kim, M.H. The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein Nat Commun, 5:2958-2958, 2014 Cited by PubMed: 24389582DOI: 10.1038/ncomms3958 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report