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4LL4

The structure of the TRX and TXNIP complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CThioredoxin-interacting proteinpolymer31535037.52UniProt (Q9H3M7)
Pfam (PF00339)
Pfam (PF02752)
In PDB
Homo sapiens (human)Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1
2B, DThioredoxinpolymer10511718.42UniProt (P10599)
Pfam (PF00085)
In PDB
Homo sapiens (human)Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP
3waterwater18.059Chemie (HOH)
Sequence modifications
A, C: 3 - 317 (UniProt: Q9H3M7)
PDBExternal DatabaseDetails
Ser 170Cys 170engineered mutation
Ser 205Cys 205engineered mutation
Ser 267Cys 267engineered mutation
B, D: 1 - 105 (UniProt: P10599)
PDBExternal DatabaseDetails
Ala 35Cys 35engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight93511.8
All*Total formula weight93511.8
*Water molecules are not included.

217705

PDB entries from 2024-03-27

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