4LKV

Determinants of lipid substrate and membrane binding for the tetraacyldisaccharide-1-phosphate 4 -kinase LpxK

4LKV の概要

• エントリーDOI: 10.2210/pdb4lkv/pdb
• 関連するPDBエントリー: 4ehw 4ehx 4ehy 4itl 4itm 4itn
• 分子名称: Tetraacyldisaccharide 4'-kinase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: p-loop containing nucleotide triphosphate hydrolase, kinase, membrane protein, transferase
• 由来する生物種: Aquifex aeolicus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 149476.67

構造登録者

Emptage, R.P.,Tonthat, N.K.,York, J.D.,Schumacher, M.A.,Zhou, P. (登録日: 2013-07-08, 公開日: 2014-07-09, 最終更新日: 2024-02-28)

• 主引用文献: Emptage, R.P.,Tonthat, N.K.,York, J.D.,Schumacher, M.A.,Zhou, P.; Structural Basis of Lipid Binding for the Membrane-embedded Tetraacyldisaccharide-1-phosphate 4'-Kinase LpxK.; J.Biol.Chem., 289:24059-24068, 2014; PubMed: 25023290; DOI: 10.1074/jbc.M114.589986

実験手法

X-RAY DIFFRACTION (3.5109 Å)