4LGD

Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5

Summary for 4LGD

Related4LG4
DescriptorSerine/threonine-protein kinase 3, Ras association domain family member 5, RASSF5, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
Functional Keywordshippo, mst autoactivation, rassf, sarah domain, dimerization, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  Q13188 Q8WWW0
Total number of polymer chains8
Total molecular weight201414.81
Authors
Luo, X.,Ni, L.,Tomchick, D.R. (deposition date: 2013-06-27, release date: 2013-09-18, Last modification date: 2018-02-28)
Primary citation
Ni, L.,Li, S.,Yu, J.,Min, J.,Brautigam, C.A.,Tomchick, D.R.,Pan, D.,Luo, X.
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5.
Structure, 21:1757-1768, 2013
PubMed: 23972470 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2013.07.008
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.05 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2494 0.7% 0.3% 11.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171313
PDB entries from 2020-11-18