4LGD

Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5

Summary for 4LGD

• Entry DOI: 10.2210/pdb4lgd/pdb
• Related: 4LG4
• Descriptor: Serine/threonine-protein kinase 3, Ras association domain family member 5, RASSF5, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
• Functional Keywords: hippo, mst autoactivation, rassf, sarah domain, dimerization, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm : Q13188 Q8WWW0
• Total number of polymer chains: 8
• Total formula weight: 201414.81

Authors

Luo, X.,Ni, L.,Tomchick, D.R. (deposition date: 2013-06-27, release date: 2013-09-18, Last modification date: 2023-09-20)

• Primary citation: Ni, L.,Li, S.,Yu, J.,Min, J.,Brautigam, C.A.,Tomchick, D.R.,Pan, D.,Luo, X.; Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5.; Structure, 21:1757-1768, 2013; PubMed: 23972470; DOI: 10.1016/j.str.2013.07.008

Experimental method

X-RAY DIFFRACTION (3.05 Å)