4LG4
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
Summary for 4LG4
Entry DOI | 10.2210/pdb4lg4/pdb |
Related | 4LGD |
Descriptor | Serine/threonine-protein kinase 3, GLYCEROL (3 entities in total) |
Functional Keywords | hippo, mst autoactivation, dimerization, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q13188 |
Total number of polymer chains | 6 |
Total formula weight | 204200.45 |
Authors | Luo, X.,Ni, L.,Tomchick, D.R. (deposition date: 2013-06-27, release date: 2013-09-18, Last modification date: 2023-09-20) |
Primary citation | Ni, L.,Li, S.,Yu, J.,Min, J.,Brautigam, C.A.,Tomchick, D.R.,Pan, D.,Luo, X. Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5. Structure, 21:1757-1768, 2013 Cited by PubMed: 23972470DOI: 10.1016/j.str.2013.07.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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