4LG4

Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5

Summary for 4LG4

Entry DOI	10.2210/pdb4lg4/pdb
Related	4LGD
Descriptor	Serine/threonine-protein kinase 3, GLYCEROL (3 entities in total)
Functional Keywords	hippo, mst autoactivation, dimerization, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : Q13188
Total number of polymer chains	6
Total formula weight	204200.45
Authors	Luo, X.,Ni, L.,Tomchick, D.R. (deposition date: 2013-06-27, release date: 2013-09-18, Last modification date: 2023-09-20)
Primary citation	Ni, L.,Li, S.,Yu, J.,Min, J.,Brautigam, C.A.,Tomchick, D.R.,Pan, D.,Luo, X. Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5. Structure, 21:1757-1768, 2013 Cited by PubMed: 23972470 DOI: 10.1016/j.str.2013.07.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.42 Å)

Structure validation