4LG4
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Serine/threonine-protein kinase 3 | polymer | 299 | 33972.0 | 6 | UniProt (Q13188) Pfam (PF00069) | Homo sapiens (human) | Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2, Serine/threonine-protein kinase Krs-1, Serine/threonine-protein kinase 3 36kDa subunit, MST2/N, Serine/threonine-protein kinase 3 20kDa subunit, MST2/C |
| 2 | G, H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 3 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 16 - 313 (UniProt: Q13188)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | expression tag |
| Asn 146 | Asp 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 203832.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 204200.4 |
