4LB9
X-ray study of human serum albumin complexed with etoposide
Summary for 4LB9
Entry DOI | 10.2210/pdb4lb9/pdb |
Related | 4L8U 4L9K 4L9Q 4LA0 4LB2 |
Descriptor | SERUM ALBUMIN, MYRISTIC ACID, (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, ... (4 entities in total) |
Functional Keywords | plasma protein, cancer, oncology drug complex, transport protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02768 |
Total number of polymer chains | 1 |
Total formula weight | 68073.26 |
Authors | Wang, Z.,Ho, J.X.,Ruble, J.,Rose, J.P.,Carter, D.C. (deposition date: 2013-06-20, release date: 2013-07-24, Last modification date: 2014-02-19) |
Primary citation | Wang, Z.M.,Ho, J.X.,Ruble, J.R.,Rose, J.,Ruker, F.,Ellenburg, M.,Murphy, R.,Click, J.,Soistman, E.,Wilkerson, L.,Carter, D.C. Structural studies of several clinically important oncology drugs in complex with human serum albumin. Biochim.Biophys.Acta, 1830:5356-5374, 2013 Cited by PubMed: 23838380DOI: 10.1016/j.bbagen.2013.06.032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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