4KRL
Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 6.0
Summary for 4KRL
Entry DOI | 10.2210/pdb4krl/pdb |
Related | 4KRM 4KRN 4KRO 4KRP |
Descriptor | Nanobody/VHH domain 7D12, Epidermal growth factor receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | cell surface receptor, glycoprotein, nanobody, vhh domain, camelid vh domain, antibody, antigen, antibody complex, transferase-immune system complex, transferase/immune system |
Biological source | Lama glama (llama) More |
Total number of polymer chains | 2 |
Total formula weight | 39746.20 |
Authors | Ferguson, K.M.,Schmitz, K.R. (deposition date: 2013-05-16, release date: 2013-08-28, Last modification date: 2023-09-20) |
Primary citation | Schmitz, K.R.,Bagchi, A.,Roovers, R.C.,van Bergen En Henegouwen, P.M.P.,Ferguson, K.M. Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains. Structure, 21:1214-1224, 2013 Cited by PubMed: 23791944DOI: 10.1016/j.str.2013.05.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.849 Å) |
Structure validation
Download full validation report