4KQ8
Structure of Recombinant Human Cytochrome P450 Aromatase
Summary for 4KQ8
| Entry DOI | 10.2210/pdb4kq8/pdb |
| Related | 3EQM 3S79 3S7S 4GL5 4GL7 |
| Descriptor | Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE, 4-ANDROSTENE-3-17-DIONE, ... (5 entities in total) |
| Functional Keywords | aromatase, androgen, estrogen, cytochrome p450, oxidoreductase, estrogen synthetase, cytochrome p450 reductase |
| Biological source | Homo sapiens (human) |
| Cellular location | Membrane; Peripheral membrane protein: P11511 |
| Total number of polymer chains | 1 |
| Total formula weight | 55683.77 |
| Authors | Ghosh, D.,Di Nardo, G.,Griswold, J. (deposition date: 2013-05-14, release date: 2013-08-21, Last modification date: 2024-02-28) |
| Primary citation | Lo, J.,Di Nardo, G.,Griswold, J.,Egbuta, C.,Jiang, W.,Gilardi, G.,Ghosh, D. Structural basis for the functional roles of critical residues in human cytochrome p450 aromatase. Biochemistry, 52:5821-5829, 2013 Cited by PubMed: 23899247DOI: 10.1021/bi400669h PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.29 Å) |
Structure validation
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