4KQ8
Structure of Recombinant Human Cytochrome P450 Aromatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 19A1 | polymer | 473 | 54685.9 | 1 | UniProt (P11511) Pfam (PF00067) | Homo sapiens (human) | Aromatase, CYPXIX, Cytochrome P-450AROM, Estrogen synthase |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 4-ANDROSTENE-3-17-DIONE | non-polymer | 286.4 | 1 | Chemie (ASD) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | E (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 45 - 503 (UniProt: P11511)
| PDB | External Database | Details |
|---|---|---|
| Met 35 | - | expression tag |
| Ala 36 | - | expression tag |
| Lys 37 | - | expression tag |
| Lys 38 | - | expression tag |
| Thr 39 | - | expression tag |
| Ser 40 | - | expression tag |
| Ser 41 | - | expression tag |
| Lys 42 | - | expression tag |
| Gly 43 | - | expression tag |
| Arg 44 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
| His 506 | - | expression tag |
| His 507 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54685.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 997.9 | |
| All* | Total formula weight | 55683.8 |
