4H9G
Probing EF-Tu with a very small brominated fragment library identifies the CCA pocket
Summary for 4H9G
Entry DOI | 10.2210/pdb4h9g/pdb |
Descriptor | Elongation factor Tu-A, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | p-loop, gtpase, gtp binding, trna binding, ribosome binding, translation |
Biological source | Thermus thermophilus |
Cellular location | Cytoplasm: P60338 |
Total number of polymer chains | 1 |
Total formula weight | 46205.86 |
Authors | Groftehauge, M.K.,Therkelsen, M.,Taaning, R.H.,Skrydstrup, T.,Morth, J.P.,Nissen, P. (deposition date: 2012-09-24, release date: 2013-09-11, Last modification date: 2024-02-28) |
Primary citation | Grftehauge, M.K.,Therkelsen, M.O.,Taaning, R.,Skrydstrup, T.,Morth, J.P.,Nissen, P. Identifying ligand-binding hot spots in proteins using brominated fragments. Acta Crystallogr.,Sect.F, 69:1060-1065, 2013 Cited by PubMed: 23989163DOI: 10.1107/S1744309113018551 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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