4GUA
Alphavirus P23pro-zbd
Summary for 4GUA
Entry DOI | 10.2210/pdb4gua/pdb |
Related | 2HWK 3GPG 3GPO 3GPQ 3GQO 3TRK |
Descriptor | Non-structural polyprotein, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | viral precursor polyprotein, protease, zinc-binding, hydrolase |
Biological source | Sindbis virus (SINV) |
Cellular location | Non-structural polyprotein: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side. P123: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side. P123': Host endosome membrane; Peripheral membrane protein; Cytoplasmic side. mRNA-capping enzyme nsP1: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side. Protease nsP2: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side. Non-structural protein 3: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side. Non-structural protein 3': Host endosome membrane; Peripheral membrane protein; Cytoplasmic side. RNA-directed RNA polymerase nsP4: Host endosome membrane; Peripheral membrane protein; Cytoplasmic side: P03317 |
Total number of polymer chains | 3 |
Total formula weight | 229719.78 |
Authors | Shin, G.,Yost, S.,Miller, M.,Marcotrigiano, J. (deposition date: 2012-08-29, release date: 2012-10-03, Last modification date: 2023-09-13) |
Primary citation | Shin, G.,Yost, S.A.,Miller, M.T.,Elrod, E.J.,Grakoui, A.,Marcotrigiano, J. Structural and functional insights into alphavirus polyprotein processing and pathogenesis. Proc.Natl.Acad.Sci.USA, 109:16534-16539, 2012 Cited by PubMed: 23010928DOI: 10.1073/pnas.1210418109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.854 Å) |
Structure validation
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