4GIE
Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP
Summary for 4GIE
Entry DOI | 10.2210/pdb4gie/pdb |
Related | 4F40 4FZI 4G5D |
Descriptor | Prostaglandin F synthase, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, chagas disease, prostaglandin d2, trypanosomiasis, eukaryotic pathogen, parasite, nadp+, nadph, rutin, bimatoprost, oxidoreductase |
Biological source | Trypanosoma cruzi |
Cellular location | Cytoplasm : Q4DJ07 |
Total number of polymer chains | 1 |
Total formula weight | 34394.48 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-08-08, release date: 2012-08-15, Last modification date: 2023-09-13) |
Primary citation | Moen, S.O.,Fairman, J.W.,Barnes, S.R.,Sullivan, A.,Nakazawa-Hewitt, S.,Van Voorhis, W.C.,Staker, B.L.,Lorimer, D.D.,Myler, P.J.,Edwards, T.E. Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71:609-614, 2015 Cited by PubMed: 25945716DOI: 10.1107/S2053230X15006883 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
Download full validation report