4GIE

Crystal structure of prostaglandin F synthase from Trypanosoma cruzi bound to NADP

4GIE の概要

• エントリーDOI: 10.2210/pdb4gie/pdb
• 関連するPDBエントリー: 4F40 4FZI 4G5D
• 分子名称: Prostaglandin F synthase, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, chagas disease, prostaglandin d2, trypanosomiasis, eukaryotic pathogen, parasite, nadp+, nadph, rutin, bimatoprost, oxidoreductase
• 由来する生物種: Trypanosoma cruzi
• 細胞内の位置: Cytoplasm : Q4DJ07
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34394.48

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-08-08, 公開日: 2012-08-15, 最終更新日: 2023-09-13)

• 主引用文献: Moen, S.O.,Fairman, J.W.,Barnes, S.R.,Sullivan, A.,Nakazawa-Hewitt, S.,Van Voorhis, W.C.,Staker, B.L.,Lorimer, D.D.,Myler, P.J.,Edwards, T.E.; Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.; Acta Crystallogr F Struct Biol Commun, 71:609-614, 2015; PubMed: 25945716; DOI: 10.1107/S2053230X15006883

実験手法

X-RAY DIFFRACTION (1.25 Å)