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4G0A

Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5'-GG Sequence for RTPase activity

Summary for 4G0A
Entry DOI10.2210/pdb4g0a/pdb
DescriptorNon-structural protein 2, RNA (5'-R(P*GP*GP*U)-3'), CHLORIDE ION, ... (5 entities in total)
Functional Keywordsrna triphosphatase, rna binding, hydrolase activity, nucleotide binding, metal ion binding, host cell cytoplasm, hydrolase-rna complex, hydrolase/rna
Biological sourceSimian 11 rotavirus (RV-A)
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Cellular locationHost cytoplasm (Potential): Q03243
Total number of polymer chains8
Total formula weight150444.31
Authors
Hu, L.,Prasad, B.V.V. (deposition date: 2012-07-09, release date: 2012-08-22, Last modification date: 2024-02-28)
Primary citationHu, L.,Chow, D.C.,Patton, J.T.,Palzkill, T.,Estes, M.K.,Prasad, B.V.
Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
J.Virol., 86:10547-10557, 2012
Cited by
PubMed: 22811529
DOI: 10.1128/JVI.01201-12
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.0995 Å)
Structure validation

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