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4G0A

Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5'-GG Sequence for RTPase activity

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Non-structural protein 2polymer31736618.34UniProt (Q03243)
Pfam (PF21067)
Pfam (PF02509)
Simian 11 rotavirus (RV-A)NSP2, NCVP3, Non-structural RNA-binding protein 35, NS35
2E, F, G, H
(E, F, G, H)
RNA (5'-R(P*GP*GP*U)-3')polymer3951.64Synthetic construct
3I, J, K, M
(A, B, C, D)
CHLORIDE IONnon-polymer35.54Chemie (CL)
4L
(C)
SODIUM IONnon-polymer23.01Chemie (NA)
5N, O, P, Q, R...
(A, B, C, D, E...)
waterwater18.01155Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight150279.5
Non-Polymers*Number of molecules5
Total formula weight164.8
All*Total formula weight150444.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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