4FRC

Carbonic Anhydrase II in complex with N'-sulfamoylpyrrolidine-1-carboximidamide

Summary for 4FRC

• Entry DOI: 10.2210/pdb4frc/pdb
• Related: 3M04 3M14 4FPT 4FU5 4FVN 4FVO
• Descriptor: Carbonic anhydrase 2, MERCURIBENZOIC ACID, ZINC ION, ... (6 entities in total)
• Functional Keywords: 10 stranded twisted beta-sheets, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29946.55

Authors

Di Pizio, A.,Heine, A.,Klebe, G. (deposition date: 2012-06-26, release date: 2013-07-17, Last modification date: 2023-09-13)

• Primary citation: Di Pizio, A.,Schulze Wischeler, J.,Haake, M.,Heine, A.,Supuran, C.,Klebe, G.; High resolution crystal structures of Carbonic Anhydrase II in complex with novel sulfamide binders; To be Published,

Experimental method

X-RAY DIFFRACTION (0.98 Å)