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4FPT

Carbonic Anhydrase II in complex with ethyl (2Z,4R)-2-(sulfamoylimino)-1,3-thiazolidine-4-carboxylate

Summary for 4FPT
Entry DOI10.2210/pdb4fpt/pdb
Related3M04 3M14 4FRC 4FU5 4FVN 4FVO
DescriptorCarbonic anhydrase 2, MERCURIBENZOIC ACID, ZINC ION, ... (7 entities in total)
Functional Keywords10 stranded twisted beta-sheets, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm: P00918
Total number of polymer chains1
Total formula weight30177.83
Authors
Di Pizio, A.,Heine, A.,Klebe, G. (deposition date: 2012-06-22, release date: 2013-07-03, Last modification date: 2023-09-13)
Primary citationDi Pizio, A.,Schulze Wischeler, J.,Haake, M.,Heine, A.,Klebe, G.
High resolution crystal structures of Carbonic Anhydrase II in complex with novel sulfamide binders
To be Published,
Experimental method
X-RAY DIFFRACTION (0.98 Å)
Structure validation

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