4FVN
Carbonic Anhydrase II in complex with N-(tetrahydropyrimidin-2(1H)-ylidene)sulfuric diamide
Summary for 4FVN
Entry DOI | 10.2210/pdb4fvn/pdb |
Related | 4FPT 4FRC 4FU5 4FVO |
Descriptor | Carbonic anhydrase 2, MERCURIBENZOIC ACID, ZINC ION, ... (6 entities in total) |
Functional Keywords | 10 stranded twisted beta-sheets, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 30010.65 |
Authors | Di Pizio, A.,Heine, A.,Klebe, G. (deposition date: 2012-06-29, release date: 2013-07-17, Last modification date: 2023-09-13) |
Primary citation | Di Pizio, A.,Schulze Wischeler, J.,Haake, M.,Heine, A.,Supuran, C.,Klebe, G. HIgh resolution crystal structures of Carbonic Anhydrase II in complex with novel sulfamide binders To be Published, |
Experimental method | X-RAY DIFFRACTION (1.05 Å) |
Structure validation
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