4FF6
Mycobacterium tuberculosis DprE1 in complex with CT325 - monoclinic crystal form
Summary for 4FF6
Entry DOI | 10.2210/pdb4ff6/pdb |
Related | 4FDN 4FDO 4FDP 4FEH |
Descriptor | Probable decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, 3-(hydroxyamino)-N-[(1R)-1-phenylethyl]-5-(trifluoromethyl)benzamide, ... (5 entities in total) |
Functional Keywords | alpha+beta, oxidoreductase, decaprenylphosphoryl-beta-d-ribose, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 107209.62 |
Authors | Batt, S.M.,Besra, G.S.,Futterer, K. (deposition date: 2012-05-31, release date: 2012-07-04, Last modification date: 2023-09-13) |
Primary citation | Batt, S.M.,Jabeen, T.,Bhowruth, V.,Quill, L.,Lund, P.A.,Eggeling, L.,Alderwick, L.J.,Futterer, K.,Besra, G.S. Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors. Proc.Natl.Acad.Sci.USA, 109:11354-11359, 2012 Cited by PubMed: 22733761DOI: 10.1073/pnas.1205735109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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