4FDP
Mycobacterium tuberculosis DprE1 - monoclinic crystal form
Summary for 4FDP
| Entry DOI | 10.2210/pdb4fdp/pdb |
| Related | 4FDN 4FDO |
| Descriptor | oxidoreductase DprE1, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ... (4 entities in total) |
| Functional Keywords | alpha+beta, oxidoreductase, decaprenylphosphoryl-beta-d-ribose |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 2 |
| Total formula weight | 106422.85 |
| Authors | Batt, S.M.,Besra, G.S.,Futterer, K. (deposition date: 2012-05-29, release date: 2012-07-04, Last modification date: 2024-02-28) |
| Primary citation | Batt, S.M.,Jabeen, T.,Bhowruth, V.,Quill, L.,Lund, P.A.,Eggeling, L.,Alderwick, L.J.,Futterer, K.,Besra, G.S. Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors. Proc.Natl.Acad.Sci.USA, 109:11354-11359, 2012 Cited by PubMed: 22733761DOI: 10.1073/pnas.1205735109 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.23 Å) |
Structure validation
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