4FEH

Mycobacterium tuberculosis DprE1 - hexagonal crystal form

Summary for 4FEH

Entry DOI	10.2210/pdb4feh/pdb
Related	4FDN 4FDO 4FDP 4FF6
Descriptor	oxidoreductase DprE1, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
Functional Keywords	alpha+beta, oxidoreductase, decaprenylphosphoryl-beta-d-ribose
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	53176.88
Authors	Batt, S.M.,Besra, G.S.,Futterer, K. (deposition date: 2012-05-30, release date: 2012-07-04, Last modification date: 2024-04-03)
Primary citation	Batt, S.M.,Jabeen, T.,Bhowruth, V.,Quill, L.,Lund, P.A.,Eggeling, L.,Alderwick, L.J.,Futterer, K.,Besra, G.S. Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors. Proc.Natl.Acad.Sci.USA, 109:11354-11359, 2012 Cited by PubMed: 22733761 DOI: 10.1073/pnas.1205735109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.035 Å)

Structure validation