4F0A
Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8
Summary for 4F0A
Entry DOI | 10.2210/pdb4f0a/pdb |
Related | 1IJY |
Descriptor | Frizzled-8, Protein Wnt-8, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | wnt signaling, ligand-receptor complex, wnt, frizzled, fatty acid acylation, glycosylation, signaling protein |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Multi-pass membrane protein: Q61091 Secreted, extracellular space, extracellular matrix: P28026 |
Total number of polymer chains | 2 |
Total formula weight | 52603.69 |
Authors | Janda, C.Y.,Waghray, D.,Levin, A.M.,Thomas, C.,Garcia, K.C. (deposition date: 2012-05-03, release date: 2012-06-13, Last modification date: 2020-07-29) |
Primary citation | Janda, C.Y.,Waghray, D.,Levin, A.M.,Thomas, C.,Garcia, K.C. Structural basis of Wnt recognition by Frizzled. Science, 337:59-64, 2012 Cited by PubMed: 22653731DOI: 10.1126/science.1222879 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.25 Å) |
Structure validation
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