4F0A
Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Frizzled-8 | polymer | 132 | 15061.3 | 1 | UniProt (Q61091) Pfam (PF01392) | Mus musculus (mouse) | Fz-8, mFz8 |
| 2 | B (B) | Protein Wnt-8 | polymer | 316 | 35185.9 | 1 | UniProt (P28026) Pfam (PF00110) | Xenopus laevis (clawed frog common platanna platanna) | XWnt-8 |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 5 | E (E) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 6 | F (B) | PALMITOLEIC ACID | non-polymer | 254.4 | 1 | Chemie (PAM) | |||
| 7 | G, H, I (B) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
A: 28 - 150 (UniProt: Q61091)
| PDB | External Database | Details |
|---|---|---|
| Ala 151 | - | expression tag |
| Ala 152 | - | expression tag |
| Ala 153 | - | expression tag |
| Leu 154 | - | expression tag |
| Glu 155 | - | expression tag |
| Val 156 | - | expression tag |
| Leu 157 | - | expression tag |
| Phe 158 | - | expression tag |
| Gln 159 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50247.3 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1905.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 450.6 | |
| All* | Total formula weight | 52603.7 |
