4E7K
PFV integrase Target Capture Complex (TCC-Mn), freeze-trapped prior to strand transfer, at 3.0 A resolution
Summary for 4E7K
Entry DOI | 10.2210/pdb4e7k/pdb |
Related | 3DLR 3OS2 3OY9 3OYA |
Descriptor | Pro-Pol polyprotein, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... (9 entities in total) |
Functional Keywords | protein-dna complex, tetramer, hhcc motif, endonuclease, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, virion, dna-binding, zinc-binding, viral protein, recombination, viral protein-dna complex, recombination-dna complex, recombination/dna |
Biological source | Human spumaretrovirus (SFVcpz(hu)) More |
Cellular location | Integrase: Virion (Potential). Protease/Reverse transcriptase/ribonuclease H: Host nucleus (By similarity): P14350 |
Total number of polymer chains | 5 |
Total formula weight | 109646.95 |
Authors | Maertens, G.N.,Cherepanov, P. (deposition date: 2012-03-17, release date: 2012-05-23, Last modification date: 2023-09-13) |
Primary citation | Hare, S.,Maertens, G.N.,Cherepanov, P. 3'-Processing and strand transfer catalysed by retroviral integrase in crystallo. Embo J., 31:3020-3028, 2012 Cited by PubMed: 22580823DOI: 10.1038/emboj.2012.118 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
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