4E7K
PFV integrase Target Capture Complex (TCC-Mn), freeze-trapped prior to strand transfer, at 3.0 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Pro-Pol polyprotein | polymer | 395 | 44456.7 | 2 | UniProt (P14350) Pfam (PF17921) Pfam (PF00665) Pfam (PF18103) In PDB | Human spumaretrovirus (SFVcpz(hu)) | Pr125Pol, Protease/Reverse transcriptase/ribonuclease H, p87Pro-RT-RNaseH, Protease/Reverse transcriptase, p65Pro-RT, Ribonuclease H, RNase H, Integrase, IN, p42In |
| 2 | C | DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3') | polymer | 19 | 5834.8 | 1 | synthetic DNA | ||
| 3 | D | DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3') | polymer | 17 | 5195.4 | 1 | synthetic DNA | ||
| 4 | T | DNA (5'-D(*CP*CP*CP*GP*AP*GP*GP*CP*AP*CP*GP*TP*GP*CP*TP*AP*GP*CP*AP*CP*GP*TP*GP*CP*CP*TP*CP*GP*GP*G)-3') | polymer | 30 | 9226.9 | 1 | synthetic DNA | ||
| 5 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 7 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | T | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 9 | water | water | 18.0 | 12 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 392 (UniProt: P14350)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 217 | Gly 968 | variant |
| Gly 218 | Ser 969 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 109170.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 476.5 | |
| All* | Total formula weight | 109646.9 |
