4E45
Crystal structure of the hMHF1/hMHF2 Histone-Fold Tetramer in Complex with Fanconi Anemia Associated Helicase hFANCM
Summary for 4E45
Entry DOI | 10.2210/pdb4e45/pdb |
Related | 4E44 |
Descriptor | Centromere protein S, Centromere protein X, Fanconi anemia group M protein, ... (6 entities in total) |
Functional Keywords | histone-fold, pentamer, fanconi anemia, helicase, fancm, mhf, dna binding protein-hydrolase complex, dna binding protein/hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q8N2Z9 A8MT69 Q8IYD8 |
Total number of polymer chains | 15 |
Total formula weight | 182335.39 |
Authors | Fox III, D.,Zhao, Y.,Yang, W.,Weidong, W. (deposition date: 2012-03-12, release date: 2013-03-20, Last modification date: 2023-09-13) |
Primary citation | Fox III, D.,Yan, Z.,Ling, C.,Zhao, Y.,Lee, D.Y.,Yang, W.,Weidong, W. Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA To be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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