4CCO
60S ribosomal protein L8 histidine hydroxylase (NO66 S373C) in complex with Mn(II), N-oxalylglycine (NOG) and 60S ribosomal protein L8 (RPL8 G214C) peptide fragment (complex-3)
Summary for 4CCO
Entry DOI | 10.2210/pdb4cco/pdb |
Related | 2XDV 4BU2 4BXF 4CCJ 4CCK 4CCM 4CCN 4DIQ |
Descriptor | BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE NO66, 60S RIBOSOMAL PROTEIN L8, MANGANESE (II) ION, ... (6 entities in total) |
Functional Keywords | oxidoreductase, non-heme, iron-binding, dsbh, 2-oxoglutarate, dioxygenase, jmjc domain, ribosome biogenesis, nuclear protein, rpl8, beta-hydroxylation, transcription and epigenetic regulation, signaling |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 4 |
Total formula weight | 111549.64 |
Authors | Chowdhury, R.,Schofield, C.J. (deposition date: 2013-10-23, release date: 2014-05-14, Last modification date: 2023-12-20) |
Primary citation | Chowdhury, R.,Sekirnik, R.,Brissett, N.C.,Krojer, T.,Ho, C.H.,Ng, S.S.,Clifton, I.J.,Ge, W.,Kershaw, N.J.,Fox, G.C.,Muniz, J.R.C.,Vollmar, M.,Phillips, C.,Pilka, E.S.,Kavanagh, K.L.,von Delft, F.,Oppermann, U.,McDonough, M.A.,Doherty, A.J.,Schofield, C.J. Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510:422-426, 2014 Cited by PubMed: 24814345DOI: 10.1038/nature13263 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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