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4C8K

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a partially closed complex with the artificial base pair d5SICS-dNaMTP

Summary for 4C8K
Entry DOI10.2210/pdb4c8k/pdb
Related4C8J 4C8L 4C8M 4C8N 4C8O
DescriptorDNA POLYMERASE I, THERMOSTABLE, 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*C*DOC)-3', 5'-D(*AP*AP*C*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', ... (8 entities in total)
Functional Keywordstransferase-dna complex, unnatural nucleotide, artificial nucleotide, binary complex, klentaq, transferase/dna
Biological sourceTHERMUS AQUATICUS
More
Total number of polymer chains3
Total formula weight70387.84
Authors
Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A. (deposition date: 2013-10-01, release date: 2013-12-11, Last modification date: 2023-12-20)
Primary citationBetz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A.
Structural Insights Into DNA Replication without Hydrogen Bonds.
J.Am.Chem.Soc., 135:18637-, 2013
Cited by
PubMed: 24283923
DOI: 10.1021/JA409609J
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.17 Å)
Structure validation

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