4C8K
Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in a partially closed complex with the artificial base pair d5SICS-dNaMTP
Summary for 4C8K
Entry DOI | 10.2210/pdb4c8k/pdb |
Related | 4C8J 4C8L 4C8M 4C8N 4C8O |
Descriptor | DNA POLYMERASE I, THERMOSTABLE, 5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*C*DOC)-3', 5'-D(*AP*AP*C*LHOP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3', ... (8 entities in total) |
Functional Keywords | transferase-dna complex, unnatural nucleotide, artificial nucleotide, binary complex, klentaq, transferase/dna |
Biological source | THERMUS AQUATICUS More |
Total number of polymer chains | 3 |
Total formula weight | 70387.84 |
Authors | Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A. (deposition date: 2013-10-01, release date: 2013-12-11, Last modification date: 2023-12-20) |
Primary citation | Betz, K.,Malyshev, D.A.,Lavergne, T.,Welte, W.,Diederichs, K.,Romesberg, F.E.,Marx, A. Structural Insights Into DNA Replication without Hydrogen Bonds. J.Am.Chem.Soc., 135:18637-, 2013 Cited by PubMed: 24283923DOI: 10.1021/JA409609J PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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